<p>Over-prescription and misuse of antibiotics has contributed to the global crisis of antimicrobial resistance (AMR)[1]. In order to manage this growing crisis, it is crucial that new technologies and techniques are developed to deal with infection. Infection in chronic wounds is a common problem, which is often targeted ineffectively by antibiotics. In addition, biofilms in chronic wounds contribute to prolonged morbidity. There are now alternative means of fighting infection and biofilms in chronic wounds with topical antimicrobials rather than systemic antibiotics. Wound irrigation with a topical antimicrobial is an effective technique that should be used to prevent and combat biofilms and potential infection, as well as promote healing, without contributing to the growing AMR crisis.</p>