<p>Intermittent pneumatic compression (IPC) is widely used to prevent deep vein thrombosis (DVT), yet IPC appears to have application to a broader base of lymphatic and venous disease. The intermittent nature of pulsatile external compression results in beneficial physiologic changes, including haematologic, haemodynamic, and endothelial effects. Application of IPC is a valuable adjunct to the treatment and management of patients with venous, lymphatic and arterial disease.</p>