Negative pressure wound therapy (NPWT) is a concept that has been around for over 20 years. There is now more choice, potential and possibilities for the use of the NPWT for different indications. An international group of specialist surgeons with a high level of experience of NPWT in various wound types convened to discuss the use of NPWT today. The group used their own experiences and current literature to discuss the appropriate use of traditional and single use NPWT and when and how to use traditional and single use NPWT in complement with each other and other therapies.