This case study provides an overview of a female patient who presented with ulcers in both lower limbs. Initially, she was diagnosed with arterial disease secondary to occlusion bilateral tibial, due to their multiple infectious intercurrences. This was further compounded by poor evolution to medical vascular treatment without the possibility of surgical treatment, due to infected or endovascular lesions and treatment confined to the use of advanced wound healing. A histopathological diagnosis of vasculitis could only be achieved following biopsy of the lesions. When vasculitis, which relates to blood vessel inflammation, affects small- or medium-sized blood vessels in the skin, it is called cutaneous vasculitis (British Association of Dermatologists, 2017). The clinical presentation can lead to misdiagnosis or confusion with systemic diseases and infections, such as mycoplasma. It is, therefore, essential to take into account these diseases as a differential diagnosis, as well as the experience of the multidisciplinary team.