<p>Background: This paper describes the validation of a ‘condition-specific’ quality of life (QoL) assessment tool for lymphoedema of the limbs (LYMQOL). Aims: To ascertain whether the tool could accurately assess QoL in this patient group. Methods: Face and content validity were assessed by patient questionnaires; criterion validity by comparison with European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire – Core 30 questions (EORTC QLQ-C30); internal validity by Cronbach’s Alpha and split half-testing of each domain; reliability by the test-retest method; construct validity by comparing LYMQOL score with initial limb volume and responsiveness by measuring changes in score following treatment. Results: The tool was validated in a total of 209 patients. Face, content, criterion and internal validity were supported. However, there was no correlation between initial limb volume and LYMQOL score (construct validity), a finding which is similar to that from other studies. The validation of responsiveness was limited by the small numbers of responses at three and six months after the initial assessment. Conclusions: LYMQOL is a validated condition-specific QoL assessment tool which can be used for lymphoedema of the limbs both in clinical assessment and as an outcome measure. Declaration of interest: The authors are not aware of any conflicts of interest.</p>
