<p>This paper presents the results of a 5-year pressure ulcer prevention programme at The Royal Melbourne Hospital in Australia. The programme involved multiple interventions coordinated by the hospital’s Skin Integrity Committee. Three hospital-wide point prevalence surveys were used to monitor progress that showed that prevalence of hospital-acquired pressure ulcers decreased from 6.6% in 2010 to 6% in 2012 and 2.5% in 2014. The results demonstrate the effectiveness of this multifaceted programme of pressure ulcer prevention based on research and education.</p>