The M.O.I.S.T. concept was developed in 2017 by an expert group (WundDACH) and is an evolution of the T.I.M.E. clinical decision tool. M.O.I.S.T. is primarily an educational tool which builds on the existing T.I.M.E concept by incorporating new areas of knowledge and local wound therapies and their impact on wound healing – namely Oxygen balance (e.g. therapies to improve wound hypoxia) and Supporting strategies (e.g. therapies including but not limited to biologics, skin substitutes, and protease modulators). T.I.M.E. includes varying concepts of wound bed preparation and re-epithelialisation, whereas M.O.I.S.T. represents the overall concept of local treatment. A broad group of wound care specialists from the Asia-Pacific (APAC) region convened in June 2022 to discuss the M.O.I.S.T. concept. Discussions focused on how M.O.I.S.T. applies to clinical practice, as well as how best to implement and deliver this educational tool to improve local wound management.