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Advances in tissue-engineered skin substitutes

Jemma Boyle, Mayura Damanhuri
24 January 2011

<p>Large skin defects resulting from burns, trauma, congenital giant nevi, and disease can lead to skin necrosis and represent a challenge to achieving skin coverage. This article summarises the development of tissue-engineered skin substitutes, identifies key clinical landmarks, reviews some critical aspects of cell and skin biology and highlights future developments that may foster progress in engineered skin.</p>

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