Share this article

Using indocyanine green fluorescent lymphography to demonstrate lymphatic architecture

David Chang, Hiroo Suami, Kiyoshi Yamada, Roman Skoracki, Yoshihiro Kimata
14 February 2014

<p>Background: Visualisation of the lymphatic system is a challenging task. Recently, an indocyanine green (ICG) fluorescent lymphography system was developed for visualising the lymphatic vessels. ICG emits energy in the near-infrared region between 840 and 850 nm when it is bound to protein in the tissue.</p>n<p>Aim: To use ICG fluorescent lymphography to identify locations of the lymphatic vessel for lymphovenous shunt. Methods: The lymphatic anatomy in the upper extremity was investigated using ICG fluorescent lymphography in 3 healthy volunteers and 15 patients with breast cancer-related lymphoedema prior to them undergoing lymphaticovenular bypass.</p>n<p>Results: In healthy volunteers, fluorescent images of lymphatic vessels emerged at the dorsal hand as a shiny linear pattern and ran longitudinally towards the proximal arm after a few minutes. In lymphoedema patients, the lymphatic vessels could be identified at the dorsal hand, but the appearance of the lymphatic structure varied between patients.</p>n<p>Conclusions: ICG fluorescent lymphography allows for the prompt identification of the lymphatic vessels and has the potential to improve the outcomes of lymphovenous shunt operations and for use as a diagnostic tool.</p>n<p>Declaration of interest: None.</p>

Free for all healthcare professionals

Sign up to the Wounds Group journals

By clicking ‘Subscribe’, you are agreeing that the Wounds Group are able to email you periodic newsletters. You may unsubscribe from these at any time. Your info is safe with us and we will never sell or trade your details. For information please review our privacy policy.

Are you a healthcare professional? This website is for healthcare professionals only. To continue, please confirm that you are a healthcare professional below.

We use cookies responsibly to ensure that we give you the best experience on our website. If you continue without changing your browser settings, we’ll assume that you are happy to receive all cookies on this website. Read about how we use cookies.

I am not a healthcare professional.