Lymphoedema is a significant side effect of cancer treatment and can result in ongoing limb oedema and reduced quality of life. This case study highlights the challenges of managing lowerlimb lymphoedema in a 70-year-old female with a history of breast cancer, with bilateral axillary node dissection, and a recent diagnosis of Non-Hodgkin’s Lymphoma in left inguinal nodes. The challenges associated with ongoing medical complications and limited available lymphatic pathways are discussed. The ongoing relationship, developing trust and ensuring good communication between the lymphoedema therapist and the patient are essential in managing symptoms and providing relief from discomfort, to optimise quality of life.